Mouse Rpusd3 activation kit by CRISPRa

CAT#: GA211634

Rpusd3 CRISPRa kit - CRISPR gene activation of mouse RNA pseudouridylate synthase domain containing 3



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CNY 12255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Rpusd3
Locus ID 101122
Kit Components

GA211634G1, Rpusd3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA211634G2, Rpusd3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA211634G3, Rpusd3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_001033204, NM_001346511
Synonyms AI527266
Summary Catalyzes uridine to pseudouridine isomerization (pseudouridylation) of specific mitochondrial mRNAs (mt-mRNAs), a post-transcriptional modification necessary for their translation. Acts at position 390 in COXI mt-mRNA and at position 697-699 in mitochondrial COXIII mt-mRNA. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and may play a role in mitochondrial ribosome biogenesis.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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