Mouse Gadd45gip1 activation kit by CRISPRa
CAT#: GA211684
Gadd45gip1 CRISPRa kit - CRISPR gene activation of mouse growth arrest and DNA-damage-inducible, gamma interacting protein 1
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Gadd45gip1 |
Locus ID | 102060 |
Kit Components | GA211684G1, Gadd45gip1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211684G2, Gadd45gip1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211684G3, Gadd45gip1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_183358 |
Synonyms | 2310040G17Rik; AI425883; Crif1; MRP-L59; Plinp1 |
Summary | Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN506260 | Gadd45gip1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |
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