Mouse Gadd45gip1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Gadd45gip1
Locus ID	102060
Kit Components	GA211684G1, Gadd45gip1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211684G2, Gadd45gip1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211684G3, Gadd45gip1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_183358
Synonyms	2310040G17Rik; AI425883; Crif1; MRP-L59; Plinp1
Summary	Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.[UniProtKB/Swiss-Prot Function]

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