Mouse Arrdc3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Arrdc3
Locus ID	105171
Kit Components	GA211852G1, Arrdc3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211852G2, Arrdc3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211852G3, Arrdc3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001042591, NR_153410, NR_153411
Synonyms	AI450344; mKIAA1376
Summary	Adapter protein that plays a role in regulating cell-surface expression of adrenergic receptors and probably also other G protein-coupled receptors (PubMed:21982743). Plays a role in NEDD4-mediated ubiquitination and endocytosis af activated ADRB2 and subsequent ADRB2 degradation. May recruit NEDD4 to ADRB2. Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes.[UniProtKB/Swiss-Prot Function]

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