Mouse Mpig6b activation kit by CRISPRa
CAT#: GA211947
Mpig6b CRISPRa kit - CRISPR gene activation of mouse megakaryocyte and platelet inhibitory receptor G6b
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Mpig6b |
Locus ID | 106722 |
Kit Components | GA211947G1, Mpig6b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211947G2, Mpig6b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211947G3, Mpig6b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_001033221, NM_001191012 |
Synonyms | AU023871; C6orf25; Ng31 |
Summary | Inhibitory receptor that acts as a critical regulator of hematopoietic lineage differentiation, megakaryocyte function and platelet production (PubMed:23112346). Inhibits platelet aggregation and activation by agonists such as ADP and collagen-related peptide (By similarity). This regulation of megakaryocate function as well as platelet production ann activation is done through the inhibition (via the 2 ITIM motifs) of the receptors CLEC1B and GP6:FcRgamma signaling (PubMed:23112346). Appears to operate in a calcium-independent manner (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN506218 | G6b - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |