Mouse Tnfaip8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tnfaip8
Locus ID	106869
Kit Components	GA211956G1, Tnfaip8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211956G2, Tnfaip8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211956G3, Tnfaip8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001177759, NM_001177760, NM_134131, NM_001360935
Synonyms	AA987150; E130304C20Rik; ENSMUSG00000073567; Gg2-1; Gm10539; Nded; Ssc-2; Tipe
Summary	Acts as a negative mediator of apoptosis. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation (By similarity).[UniProtKB/Swiss-Prot Function]

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