Mouse Lpxn activation kit by CRISPRa
CAT#: GA211983
Lpxn CRISPRa kit - CRISPR gene activation of mouse leupaxin
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Lpxn |
Locus ID | 107321 |
Kit Components | GA211983G1, Lpxn gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211983G2, Lpxn gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211983G3, Lpxn gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_134152, NM_001361971 |
Synonyms | 4933402K05Rik; A530083L21Rik; AV278559; LDPL |
Summary | Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin-induced tyrosine phosphorylation of paxillin (PXN). May play a critical role as an adapter protein in the formation of the adhesion zone in osteoclasts. Negatively regulates B-cell antigen receptor (BCR) signaling.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN509402 | Lpxn - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |