Mouse Lpxn activation kit by CRISPRa

CAT#: GA211983

Lpxn CRISPRa kit - CRISPR gene activation of mouse leupaxin



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CNY 12255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Lpxn
Locus ID 107321
Kit Components

GA211983G1, Lpxn gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA211983G2, Lpxn gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA211983G3, Lpxn gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_134152, NM_001361971
Synonyms 4933402K05Rik; A530083L21Rik; AV278559; LDPL
Summary Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin-induced tyrosine phosphorylation of paxillin (PXN). May play a critical role as an adapter protein in the formation of the adhesion zone in osteoclasts. Negatively regulates B-cell antigen receptor (BCR) signaling.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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