Mouse Rnf144a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rnf144a
Locus ID	108089
Kit Components	GA212086G1, Rnf144a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212086G2, Rnf144a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212086G3, Rnf144a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001081977, NM_080563
Synonyms	Rnf144; Ubce7ip4; UIP4
Summary	E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates the ubiquitination and degradation of the DNA damage kinase PRKDC.[UniProtKB/Swiss-Prot Function]

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