Mouse Baiap2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Baiap2
Locus ID	108100
Kit Components	GA212089G1, Baiap2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212089G2, Baiap2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212089G3, Baiap2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001037754, NM_001037755, NM_130862
Synonyms	IRSp53; R75030
Summary	Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions.[UniProtKB/Swiss-Prot Function]

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