Mouse U2af1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	U2af1
Locus ID	108121
Kit Components	GA212096G1, U2af1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212096G2, U2af1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212096G3, U2af1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001163769, NM_024187, NM_001357907
Synonyms	35kDa; 2010107D16Rik
Summary	Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron (By similarity).[UniProtKB/Swiss-Prot Function]

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