Mouse Cdca2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cdca2
Locus ID	108912
Kit Components	GA212163G1, Cdca2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212163G2, Cdca2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212163G3, Cdca2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001110162, NM_175384
Synonyms	2610311M19Rik; AI586158
Summary	Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates (By similarity).[UniProtKB/Swiss-Prot Function]

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