Mouse Slc8a2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Slc8a2
Locus ID	110891
Kit Components	GA212366G1, Slc8a2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212366G2, Slc8a2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212366G3, Slc8a2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001347561, NM_148946
Synonyms	Ncx2
Summary	Mediates the electrogenic exchange of Ca(2+) against Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes. Contributes to cellular Ca(2+) homeostasis in excitable cells. Contributes to the rapid decrease of cytoplasmic Ca(2+) levels back to baseline after neuronal activation, and thereby contributes to modulate synaptic plasticity, learning and memory (PubMed:12818181). Plays a role in regulating urinary Ca(2+) and Na(+) excretion (PubMed:25498502).[UniProtKB/Swiss-Prot Function]

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