Mouse Dph1 activation kit by CRISPRa

CAT#: GA212466

Dph1 CRISPRa kit - CRISPR gene activation of mouse diphthamide biosynthesis 1



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CNY 12255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Dph1
Locus ID 116905
Kit Components

GA212466G1, Dph1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA212466G2, Dph1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA212466G3, Dph1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_144491
Synonyms 2310011M22Rik; 4930488F09Rik; AW551873; Dph2l1; Ovca1
Summary Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2). Acts also as a tumor suppressor in lung and breast cancers. Plays a role in embryonic growth, organogenesis and postnatal survival. When overexpressed, suppresses colony formation ability and growth rate of ovarian cancer cells (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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