Mouse Pilrb1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pilrb1
Locus ID	170741
Kit Components	GA212588G1, Pilrb1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212588G2, Pilrb1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212588G3, Pilrb1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_133209
Synonyms	Fdact; FDFACT; Pilrb
Summary	Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRB is thought to act as a cellular signaling activating receptor that associates with ITAM-bearing adapter molecules on the cell surface. Seems to associate with DAP12 and is a receptor for CD99. May be involved in target cell recognition by natural killer cells and in activation of dendritic cells.[UniProtKB/Swiss-Prot Function]

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