Mouse Bco2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Bco2
Locus ID	170752
Kit Components	GA212595G1, Bco2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212595G2, Bco2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212595G3, Bco2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_133217, NM_001359610
Synonyms	B-diox-II; Bcdo2; Bcmo2; CMO2
Summary	Asymmetrically cleaves beta-carotene at the 9',10' double bond resulting in the formation of beta-apo-10'-carotenal and beta-ionone. Besides beta-carotene, lycopene is also oxidatively cleaved. The apocarotenals formed by this enzyme may be the precursors for the biosynthesis of retinoic acid or exert unknown physiological effects.[UniProtKB/Swiss-Prot Function]

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