Mouse Tmem47 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tmem47
Locus ID	192216
Kit Components	GA212715G1, Tmem47 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212715G2, Tmem47 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212715G3, Tmem47 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_138751, NM_175771
Synonyms	3010015F07Rik; AI115536; BCMP1; Tm4sf10
Summary	Regulates cell junction organization in epithelial cells. May play a role in the transition from adherens junction to tight junction assembly. May regulate F-actin polymerization required for tight junctional localization dynamics and affect the junctional localization of PARD6B (PubMed:26990309). During podocyte differentiation may negatively regulate activity of FYN and subsequently the abundance of nephrin (PubMed:21881001).[UniProtKB/Swiss-Prot Function]

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