Mouse Hps4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Hps4
Locus ID	192232
Kit Components	GA212717G1, Hps4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212717G2, Hps4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212717G3, Hps4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_138646, NM_001359853
Synonyms	2010205O06Rik; AU040608; BLOC-3; C130020P05Rik; le; mKIAA1667
Summary	Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor (GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38.[UniProtKB/Swiss-Prot Function]

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