Mouse Kdm4b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Kdm4b
Locus ID	193796
Kit Components	GA212754G1, Kdm4b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212754G2, Kdm4b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212754G3, Kdm4b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_172132, NM_001357909
Synonyms	4732474L06Rik; Jmjd2b; mKIAA0876
Summary	Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate (By similarity).[UniProtKB/Swiss-Prot Function]

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