Mouse Thsd4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Thsd4
Locus ID	207596
Kit Components	GA212818G1, Thsd4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212818G2, Thsd4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212818G3, Thsd4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001040426, NM_172444
Synonyms	ADAMTSL-6; Adamtsl4; ADAMTSL6; AI585901; B230114P05Rik
Summary	Promotes FBN1 matrix assembly. Attenuates TGFB signaling, possibly by accelerating the sequestration of large latent complexes of TGFB or active TGFB by FBN1 microfibril assembly, thereby negatively regulating the expression of TGFB regulatory targets, such as POSTN.[UniProtKB/Swiss-Prot Function]

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