Mouse Mms22l activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mms22l
Locus ID	212377
Kit Components	GA213077G1, Mms22l gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213077G2, Mms22l gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213077G3, Mms22l gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_199467, NR_149739
Synonyms	F730047E07Rik; Gm134
Summary	Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication by promoting homologous recombination-mediated repair of replication fork-associated double-strand breaks. It may act by mediating the assembly of RAD51 filaments on ssDNA (By similarity).[UniProtKB/Swiss-Prot Function]

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