Mouse Tapbpl activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tapbpl
Locus ID	213233
Kit Components	GA213134G1, Tapbpl gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213134G2, Tapbpl gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213134G3, Tapbpl gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_145391
Synonyms	BC017613; TAPBPL-R; Tapbplr
Summary	Component of the antigen processing and presentation pathway, which binds to MHC class I coupled with beta2-microglobulin/B2M. Association between TAPBPR and MHC class I occurs in the absence of a functional peptide-loading complex (PLC). Expression seems to slow down and down-regulate MHC class I surface expression.[UniProtKB/Swiss-Prot Function]

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