Mouse Chtf18 activation kit by CRISPRa

CAT#: GA213243

Chtf18 CRISPRa kit - CRISPR gene activation of mouse CTF18, chromosome transmission fidelity factor 18



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CNY 12255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Chtf18
Locus ID 214901
Kit Components

GA213243G1, Chtf18 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA213243G2, Chtf18 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA213243G3, Chtf18 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_145409
Synonyms 6030457M03Rik; Chl12; CTF18
Summary Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated by the presence of primed DNA, replication protein A (RPA) and by proliferating cell nuclear antigen (PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loading of PCNA onto primed and gapped DNA. It also interacts with and stimulates DNA polymerase POLH (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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