Mouse Chtf18 activation kit by CRISPRa
CAT#: GA213243
Chtf18 CRISPRa kit - CRISPR gene activation of mouse CTF18, chromosome transmission fidelity factor 18
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Chtf18 |
Locus ID | 214901 |
Kit Components | GA213243G1, Chtf18 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213243G2, Chtf18 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213243G3, Chtf18 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_145409 |
Synonyms | 6030457M03Rik; Chl12; CTF18 |
Summary | Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated by the presence of primed DNA, replication protein A (RPA) and by proliferating cell nuclear antigen (PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loading of PCNA onto primed and gapped DNA. It also interacts with and stimulates DNA polymerase POLH (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN503335 | Chtf18 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |