Mouse Rab11fip3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rab11fip3
Locus ID	215445
Kit Components	GA213278G1, Rab11fip3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213278G2, Rab11fip3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213278G3, Rab11fip3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001162868, NM_001162869, NM_153140
Synonyms	Cart1; D030060O14Rik; mKIAA0665; Rab11-FIP3
Summary	Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis (By similarity). Also required for the structural integrity of the endosomal recycling compartment during interphase. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (By similarity).[UniProtKB/Swiss-Prot Function]

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