Mouse Alx1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Alx1
Locus ID	216285
Kit Components	GA213340G1, Alx1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213340G2, Alx1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213340G3, Alx1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_172553
Synonyms	AI314867; C130005I02; Cart1
Summary	Sequence-specific DNA-binding transcription factor that binds palindromic sequences within promoters and may activate or repress the transcription of a subset of genes (PubMed:12929931). Most probably regulates the expression of genes involved in the development of mesenchyme-derived craniofacial structures. Early on in development, it plays a role in forebrain mesenchyme survival (PubMed:8673125). May also induce epithelial to mesenchymal transition (EMT) through the expression of SNAI1 (By similarity).[UniProtKB/Swiss-Prot Function]

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