Mouse Cd300a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cd300a
Locus ID	217303
Kit Components	GA213453G1, Cd300a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213453G2, Cd300a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213453G3, Cd300a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001347654, NM_170758, NM_001359812
Synonyms	B230315M08Rik; Clm8; LMIR1; MAIR-I; MAIR-Ia; mcpir1; MMAC8; Pigr4
Summary	Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation (PubMed:12874256, PubMed:12893283, PubMed:16339535). Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6 (By similarity).[UniProtKB/Swiss-Prot Function]

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