Mouse Tdrd3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tdrd3
Locus ID	219249
Kit Components	GA213604G1, Tdrd3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213604G2, Tdrd3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213604G3, Tdrd3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001253755, NM_172605
Synonyms	4732418C03Rik; 6720468N18
Summary	Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins (By similarity).[UniProtKB/Swiss-Prot Function]

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