Mouse Marchf6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Marchf6
Locus ID	223455
Kit Components	GA213615G1, Marchf6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213615G2, Marchf6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213615G3, Marchf6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_172606
Synonyms	3830408G03; F830029L24Rik; mKIAA0597
Summary	E3 ubiquitin-protein ligase that promotes 'Lys-48'-linked ubiquitination of target proteins, leading to their proteasomal degradation. Promotes ubiquitination of DIO2, leading to its degradation. Promotes ubiquitination of SQLE, leading to its degradation. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May cooperate with UBE2G1.[UniProtKB/Swiss-Prot Function]

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