Mouse Cerk activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cerk
Locus ID	223753
Kit Components	GA213638G1, Cerk gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213638G2, Cerk gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213638G3, Cerk gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_145475
Synonyms	AI848610; D330016D08Rik; mKIAA1646
Summary	Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate (PubMed:16269826). Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines (PubMed:16269826). Shows a greater preference for D-erythro isomer of ceramides (By similarity). Binds phosphoinositides (By similarity).[UniProtKB/Swiss-Prot Function]

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