Mouse Muc20 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Muc20
Locus ID	224116
Kit Components	GA213676G1, Muc20 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213676G2, Muc20 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213676G3, Muc20 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001145874, NM_146071
Synonyms	BC026367
Summary	May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression (By similarity).[UniProtKB/Swiss-Prot Function]

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