Mouse Ilrun activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ilrun
Locus ID	224647
Kit Components	GA213706G1, Ilrun gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213706G2, Ilrun gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213706G3, Ilrun gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001033279, NM_001044719, NM_001271511
Synonyms	AU020189; C030010A15; C80239
Summary	Negative regulator of innate antiviral response. Blocks IRF3-dependent cytokine production such as IFNA, IFNB and TNF. Interacts with IRF3 and inhibits IRF3 recruitment to type I IFN promoter sequences while also reducing nuclear levels of the coactivators EP300 and CREBBP.[UniProtKB/Swiss-Prot Function]

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