Mouse Camk1d activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Camk1d
Locus ID	227541
Kit Components	GA213933G1, Camk1d gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213933G2, Camk1d gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213933G3, Camk1d gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001290374, NM_001290375, NM_001290376, NM_177343
Synonyms	A630059D12Rik; CaMKIdelta; CKLiK; E030025C11Rik; mCKLiK
Summary	Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocampal neurons. In neutrophil cells, required for cytokine-induced proliferative responses and activation of the respiratory burst. Activates the transcription factor CREB1 in hippocampal neuron nuclei. May play a role in apoptosis of erythroleukemia cells. In vitro, phosphorylates transcription factor CREM isoform Beta (By similarity). Isoform 1 but not isoform 2 activates CREB1.[UniProtKB/Swiss-Prot Function]

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