Mouse Trub2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Trub2
Locus ID	227682
Kit Components	GA213956G1, Trub2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213956G2, Trub2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213956G3, Trub2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001290495, NM_001290496, NM_145520, NR_027344, NR_110962
Synonyms	G430055L02Rik
Summary	Minor enzyme contributing to the isomerization of uridine to pseudouridine (pseudouridylation) of specific mitochondrial mRNAs (mt-mRNAs) such as COXI and COXIII mt-mRNAs. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation.[UniProtKB/Swiss-Prot Function]

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