Mouse Zgpat activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Zgpat
Locus ID	229007
Kit Components	GA214056G1, Zgpat gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214056G2, Zgpat gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214056G3, Zgpat gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001048148, NM_144894
Synonyms	1500006I01Rik; BC021513
Summary	Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor (By similarity).[UniProtKB/Swiss-Prot Function]

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