Mouse Eif2a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Eif2a
Locus ID	229317
Kit Components	GA214066G1, Eif2a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214066G2, Eif2a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214066G3, Eif2a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001005509
Synonyms	D030048D22; D3Ertd194e
Summary	Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.[UniProtKB/Swiss-Prot Function]

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