Mouse Amigo1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Amigo1
Locus ID	229715
Kit Components	GA214108G1, Amigo1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214108G2, Amigo1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214108G3, Amigo1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001004293, NM_001287093, NM_146137
Synonyms	ali2; Amigo
Summary	Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain (By similarity). Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 (PubMed:22056818).[UniProtKB/Swiss-Prot Function]

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