Mouse Cdc14a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cdc14a
Locus ID	229776
Kit Components	GA214112G1, Cdc14a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214112G2, Cdc14a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214112G3, Cdc14a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001080818, NM_001173553, NM_001355646
Synonyms	A830059A17Rik; Cdc14; CDC14a1; CDC14A2
Summary	Dual-specificity phosphatase. Required for centrosome separation and productive cytokinesis during cell division. Dephosphorylates SIRT2 around early anaphase. May dephosphorylate the APC subunit FZR1/CDH1, thereby promoting APC-FZR1 dependent degradation of mitotic cyclins and subsequent exit from mitosis (By similarity). Required for normal hearing (PubMed:29293958).[UniProtKB/Swiss-Prot Function]

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