Mouse Cox18 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cox18
Locus ID	231430
Kit Components	GA214257G1, Cox18 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214257G2, Cox18 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214257G3, Cox18 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001033310, NM_001163456, NR_028088
Synonyms	BC038311
Summary	Mitochondrial membrane insertase required for the translocation of the C-terminus of cytochrome c oxidase subunit II (MT-CO2/COX2) across the mitochondrial inner membrane. Plays a role in MT-CO2/COX2 maturation following the COX20-mediated stabilization of newly synthesized MT-CO2/COX2 protein and before the action of the metallochaperones SCO1/2. Essential for the assembly and stability of the mitochondrial respiratory chain complex IV (also known as cytochrome c oxidase).[UniProtKB/Swiss-Prot Function]

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