Mouse Cxcl17 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cxcl17
Locus ID	232983
Kit Components	GA214407G1, Cxcl17 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214407G2, Cxcl17 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214407G3, Cxcl17 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_153576
Synonyms	VCC-1; Vcc1
Summary	Chemokine that acts as chemoattractant for monocytes, macrophages and dendritic cells (PubMed:24973458). Plays a role in angiogenesis and possibly in the development of tumors (PubMed:16989774). Acts as an anti-inflammatory in the stomach. May play a role in the innate defense against infections. Activates the C-X-C chemokine receptor GPR35 to induce a rapid and transient rise in the level of intracellular calcium ions.[UniProtKB/Swiss-Prot Function]

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