Mouse Tufm activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tufm
Locus ID	233870
Kit Components	GA214485G1, Tufm gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214485G2, Tufm gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214485G3, Tufm gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001163713, NM_172745
Synonyms	2300002G02Rik; C76308; C76389; EF-TuMT; EFTU
Summary	Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays also a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochondria and serves as a checkpoint of the RIG-I/DDX58-MAVS pathway. In turn, inhibits RLR-mediated type I interferon while promoting autophagy.[UniProtKB/Swiss-Prot Function]

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