Mouse Setd1a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Setd1a
Locus ID	233904
Kit Components	GA214495G1, Setd1a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214495G2, Setd1a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214495G3, Setd1a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_178029, NM_010940
Synonyms	BC010250; KMT2F; mKIAA0339; mNSC1; Nsccn1
Summary	Histone methyltransferase that specifically methylates 'Lys-4' of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring 'Lys-9' residue is already methylated. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. The non-overlapping localization with SETD1B suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression.[UniProtKB/Swiss-Prot Function]

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