Mouse Cbr4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cbr4
Locus ID	234309
Kit Components	GA214518G1, Cbr4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214518G2, Cbr4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214518G3, Cbr4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_145595
Synonyms	A730083J17Rik; BC009118
Summary	The heterotetramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis. Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD. The homotetramer has NADPH-dependent quinone reductase activity. Both homotetramer and the heterotetramer have broad in vitro substrate specificity and can reduce 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones.[UniProtKB/Swiss-Prot Function]

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