Mouse Tmtc3 activation kit by CRISPRa

CAT#: GA214730

Tmtc3 CRISPRa kit - CRISPR gene activation of mouse transmembrane and tetratricopeptide repeat containing 3



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CNY 12255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Tmtc3
Locus ID 237500
Kit Components

GA214730G1, Tmtc3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA214730G2, Tmtc3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA214730G3, Tmtc3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_001033332, NM_001110013
Synonyms 9130014E20Rik; B130008E12Rik; mSmile
Summary Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O-mannosyl-transferase on other proteins such as PDIA3. Involved in the positive regulation of proteasomal protein degradation in the endoplasmic reticulum (ER), and the control of ER stress response.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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