Mouse Vash1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Vash1
Locus ID	238328
Kit Components	GA214789G1, Vash1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214789G2, Vash1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214789G3, Vash1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_177354
Synonyms	AI834978; D930046M13Rik; G630009D10Rik
Summary	Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function (PubMed:29146868). Acts as an angiogenesis inhibitor: inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis (PubMed:19204325). This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts (By similarity).[UniProtKB/Swiss-Prot Function]

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