Mouse Ttll8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ttll8
Locus ID	239591
Kit Components	GA214864G1, Ttll8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214864G2, Ttll8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214864G3, Ttll8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_172818, NM_001357736
Synonyms	1700019P01Rik; 4933401B17
Summary	Monoglycylase which modifies both tubulin and non-tubulin proteins, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues of target proteins. Monoglycylates tubulin, with a preference for alpha-tubulin toward beta-tubulin. Has the ability to modify non-tubulin proteins such as ANP32A, ANP32B, SET and NCL. Involved in the side-chain initiation step of the glycylation reaction by adding a single glycine chain to generate monoglycine side chains. Not involved in elongation step of the polyglycylation reaction.[UniProtKB/Swiss-Prot Function]

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