Mouse Peli3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Peli3
Locus ID	240518
Kit Components	GA214929G1, Peli3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214929G2, Peli3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214929G3, Peli3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001347422, NM_172835
Synonyms	6030441F14Rik; A930011L17; BC028931
Summary	E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1. Can activate AP1/JUN and ELK1. Not required for NF-kappa-B activation.[UniProtKB/Swiss-Prot Function]

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