Mouse Slc5a12 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Slc5a12
Locus ID	241612
Kit Components	GA215005G1, Slc5a12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA215005G2, Slc5a12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA215005G3, Slc5a12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001003915, NM_001177624
Synonyms	AI315119; D630015G19; SMCT2
Summary	Acts as an electroneutral and low-affinity sodium (Na(+))-dependent sodium-coupled solute transporter. Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, nicotinate, propionate, butyrate and beta-D-hydroxybutyrate. May be responsible for the first step of reabsorption of monocarboxylates from the lumen of the proximal tubule of the kidney and the small intestine. May play also a role in monocarboxylates transport in the retina. Mediates electroneutral uptake of lactate, with a stoichiometry of 2 Na(+) for each lactate.[UniProtKB/Swiss-Prot Function]

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