Mouse Rgp1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rgp1
Locus ID	242406
Kit Components	GA215043G1, Rgp1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA215043G2, Rgp1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA215043G3, Rgp1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_172866
Synonyms	1110029E03Rik; AI527196; F730001J03; mKIAA0258
Summary	The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP and may thereby required for efficient fusion of endosome-derived vesicles with the Golgi compartment. The RIC1-RGP1 complex participates in the recycling of mannose-6-phosphate receptors.[UniProtKB/Swiss-Prot Function]

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