Mouse Wdr59 activation kit by CRISPRa
CAT#: GA216291
Wdr59 CRISPRa kit - CRISPR gene activation of mouse WD repeat domain 59
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Wdr59 |
Locus ID | 319481 |
Kit Components | GA216291G1, Wdr59 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216291G2, Wdr59 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216291G3, Wdr59 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_001170742, NM_001170743, NM_176923 |
Synonyms | 5430401O09Rik; Cdw12 |
Summary | As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex. It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN519371 | Wdr59 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |