Mouse Dennd4c activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dennd4c
Locus ID	329877
Kit Components	GA216776G1, Dennd4c gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216776G2, Dennd4c gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216776G3, Dennd4c gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001081014, NM_184088
Synonyms	1700065A05Rik; AA420392; RP24-468M3.1
Summary	Guanine nucleotide exchange factor (GEF) activating RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB10 into its active GTP-bound form. Thereby, stimulates SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane in response to insulin.[UniProtKB/Swiss-Prot Function]

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