Mouse Ttll10 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ttll10
Locus ID	330010
Kit Components	GA216786G1, Ttll10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216786G2, Ttll10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216786G3, Ttll10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_029264, NM_001368641
Synonyms	4833412E22Rik; 4930595O22Rik; AU022799; BC042775; Ttll5
Summary	Polyglycylase which modifies both tubulin and non-tubulin proteins, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues of target proteins. Polyglycylates alpha-tubulin and beta-tubulin, but is not able to initiate glycylation and only has activity toward monoglycylated tubulin. Has the ability to polyglycylate non-tubulin proteins such as NAP1; in this case it can initiate glycylation and does not require preliminary monoglycylation by another glycylase.[UniProtKB/Swiss-Prot Function]

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