Mouse Morc3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Morc3
Locus ID	338467
Kit Components	GA216943G1, Morc3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216943G2, Morc3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216943G3, Morc3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001045529
Synonyms	1110051N18Rik; AI452146; BF318192; D16Jhu32e; NXP2; Zcwcc3
Summary	Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism (By similarity). Sumoylated MORC3-NBs can also associate with PML-NBs (By similarity). Recruits TP53 and SP100 to PML-NBs, thus regulating TP53 activity (PubMed:17332504). Binds RNA in vitro (By similarity).[UniProtKB/Swiss-Prot Function]

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